Controlled Trials in Children: Quantity, Methodological Quality and Descriptive Characteristics of Pediatric Controlled Trials Published 1948-2006
نویسندگان
چکیده
منابع مشابه
Controlled Trials in Children: Quantity, Methodological Quality and Descriptive Characteristics of Pediatric Controlled Trials Published 1948-2006
BACKGROUND The objective of this study was to describe randomized controlled trials (RCTs) and controlled clinical trials (CCTs) in child health published between 1948 and 2006, in terms of quantity, methodological quality, and publication and trial characteristics. We used the Trials Register of the Cochrane Child Health Field for overall trends and a sample from this to explore trial characte...
متن کاملBlindness in Randomized Controlled Trials
In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...
متن کاملA descriptive analysis of a representative sample of pediatric randomized controlled trials published in 2007
BACKGROUND Randomized controlled trials (RCTs) are the gold standard for trials assessing the effects of therapeutic interventions; therefore it is important to understand how they are conducted. Our objectives were to provide an overview of a representative sample of pediatric RCTs published in 2007 and assess the validity of their results. METHODS We searched Cochrane Central Register of Co...
متن کامل10-year trend in quantity and quality of pediatric randomized controlled trials published in mainland China: 2002–2011
BACKGROUND Quality assessment of pediatric randomized controlled trials (RCTs) in China is limited. The aim of this study was to evaluate the quantitative trends and quality indicators of RCTs published in mainland China over a recent 10-year period. METHODS We individually searched all 17 available pediatric journals published in China from January 1, 2002 to December 30, 2011 to identify RC...
متن کاملParticipation of epidemiologists and/or biostatisticians and methodological quality of published controlled clinical trials.
STUDY OBJECTIVE This study assessed several methodological aspects related to the quality of published controlled clinical trials (CCTs) in relation to the participation of an epidemiologist/biostatistician (E/B). DESIGN Handsearch of CCTs published in four medical leading journals for 1993-1995. METHODS Quality variables, abstracted from a review, were related to authors' specialties. Five...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0013106